THE DISTRIBUTION OF KETONE BODIES IN TISSUES

Utilization of ketone bodies by mammalian tissues.

It is now well established that ketone bodies (acetoacetate and D-3-hydroxybutyrate) are metabolized by many mammalian tissues and that the rate of utilization is mainly dependent on their availability in the circulation. The aim in this contribution is to summarize briefly the pathways of ketone-body metabolism and to discuss the role of ketone bodies m various tissues. For a detailed review o...

The determination of ketone bodies.

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Ketone aldehydes in tissues.

Metabolism of ketone bodies in pregnant sheep.

A combination of isotope-dilution and arteriovenous-difference techniques was used to determine the significance of ketones to energy homoeostasis in fasted pregnant ewes. 2. There was incomplete interconversion of D(-) 3-hydroxybutyrate (3HB) and acetoacetate (AcAc) and therefore neither entry rate nor oxidation of total ketone bodies could be estimated by assuming circulating ketone bodies re...

Clinical and Biochemical Studies on the Basis of Ketone Bodies in Cattle : I. Blood Ketone Bodies in Normal Dairy Cattle